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Paolo Pierobon is a physicist by training,CNRS research director at Institut Cochin where he leads the Mechanics of Immune Cells sub-team within the Immune cell signaling and retroviral infection team at Institut Cochin headed by C. Randriamampita. The team’s research aims at understanding how mechanics influence the action of immune system cells, in particular lymphocyte migration and activation. Experimental approaches combine cell and tissue imaging, micro-fluidics, single-cell analysis technologies and genetically modified mouse models. The team’s research lies at the interface between physics of living systems, immunology and cell biology, and is carried out in collaboration with numerous teams within the Institute in France and internationally.